Early Necrotizing Fasciitis

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Children with GAS infection who appear unusually ill require aggressive inpatient evaluation and treatment. Streptococcal infections superimposed on varicella infection (chicken pox) represent a particularly high-risk situation. Aggressive treatment of such infections and close follow-up care are essential.

European surveillance in Italy found that 32% of group A streptococcal isolates exhibited resistance to macrolides. France has reported a steady escalation of erythromycin resistance in group A streptococci (GAS), reaching 23% to date. Portugal identified 11% of GAS isolates as resistant to macrolides. Resistance in other European countries during the 1990s fell between 1% and 7%. [ 36 ]

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